| Rank | Title | Weekend |
|---|---|---|
| 1 | Unbreakable / 2000 | £2,004,890 |
| 2↔ (2) | Meet the Parents / 2000 | £1,116,551 |
| 3↔ (3) | 102 Dalmatians / 2000 | £1,019,610 |
| 4↓ (1) | How the Grinch Stole Christmas / 2000 | £757,311 |
| 5↓ (4) | The Family Man / 2000 | £436,494 |
| 6↔ (6) | Charlie's Angels / 2000 | £261,653 |
| 7↓ (5) | Pokémon: The Movie 2000 / 2000 | £211,947 |
| 8↓ (7) | The 6th Day / 2000 | £157,084 |
| 9 ⇅ (re) | Bring It On / 2000 | £59,784 |
| 10↓ (9) | Billy Elliot / 2000 | £58,186 |
| 11↓ (8) | What Lies Beneath / 2000 | £55,845 |
| 12 ⇅ | Raju Chacha / 2000 | £38,509 |
| 13↓ (11) | Merlin the Return / 2000 | £22,373 |
| 14↓ (10) | Coyote Ugly / 2000 | £21,655 |
| 15↓ (12) | Small Time Crooks / 2000 | £16,982 |
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