| Rank | Title | Weekend |
|---|---|---|
| 1 | Cast Away / 2000 | £2,807,312 |
| 2↓ (1) | Unbreakable / 2000 | £1,282,070 |
| 3↓ (2) | Meet the Parents / 2000 | £1,107,549 |
| 4↔ (4) | Crouching Tiger, Hidden Dragon / 2001 | £660,266 |
| 5↓ (3) | 102 Dalmatians / 2000 | £561,190 |
| 6↔ (6) | The Family Man / 2000 | £250,319 |
| 7↓ (5) | How the Grinch Stole Christmas / 2000 | £245,049 |
| 8 | Lost Souls / 2001 | £217,276 |
| 9↓ (7) | Bless the Child / 2001 | £211,588 |
| 10 | Under Suspicion / 2001 | £187,708 |
| 11↓ (9) | Pokémon: The Movie 2000 / 2000 | £144,355 |
| 12↓ (8) | Charlie's Angels / 2000 | £128,188 |
| 13 | Sexy Beast / 2000 | £96,162 |
| 14↓ (11) | Bring It On / 2000 | £71,552 |
| 15 ⇅ (re) | Little Nicky / 2000 | £61,208 |
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