| Rank | Title | Weekend |
|---|---|---|
| 1 | The Hitchhikers Guide to the Galaxy / 2005 | £3,298,262 |
| 2 | xXx 2: The Next Level / 2005 | £920,506 |
| 3↓ (1) | The Interpreter / 2005 | £749,529 |
| 4↓ (3) | The Wedding Date / 2005 | £672,417 |
| 5↓ (2) | The Amityville Horror / 2005 | £547,889 |
| 6↓ (4) | Guess Who / 2005 | £415,970 |
| 7↓ (5) | Sahara / 2005 | £288,427 |
| 8↓ (6) | Valiant / 2005 | £238,246 |
| 9↓ (8) | Robots / 2005 | £164,115 |
| 10↔ (10) | WAQT: The Race Against Time / 2005 | £149,054 |
| 11↓ (7) | Hitch / 2005 | £138,668 |
| 12↔ (12) | Downfall / 2005 | £106,446 |
| 13 | Kaal / 2005 | £101,649 |
| 14↓ (13) | Beauty Shop / 2005 | £73,859 |
| 15↓ (9) | Be Cool / 2005 | £59,904 |
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