| Rank | Title | Weekend |
|---|---|---|
| 1 | Chicken Little / 2005 | £3,173,867 |
| 2 | Final Destination 3 / 2006 | £2,219,978 |
| 3 | Big Mommas House 2 / 2006 | £1,735,839 |
| 4↓ (2) | Walk the Line / 2006 | £1,150,472 |
| 5↓ (1) | Zathura: A Space Adventure / 2006 | £585,485 |
| 6↓ (4) | Munich / 2006 | £521,566 |
| 7↓ (3) | Fun With Dick and Jane / 2006 | £400,776 |
| 8↓ (5) | Derailed / 2005 | £387,238 |
| 9↓ (6) | Brokeback Mountain / 2006 | £367,113 |
| 10↓ (8) | Memoirs of a Geisha / 2005 | £279,239 |
| 11↓ (7) | Rumor Has It / 2006 | £179,411 |
| 12↓ (9) | The Chronicles of Narnia: The Lion the Witch and the Wardrobe / 2005 | £165,455 |
| 13↔ (13) | Hidden / 2005 | £132,740 |
| 14 ⇅ (re) | Rang De Basanti / 2006 | £90,814 |
| 15 | Proof / 2005 | £89,115 |
| 16 | The Little Polar Bear 2: The Mysterious Island / 2006 | £80,915 |
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