| Rank | Title | Weekend |
|---|---|---|
| 1↔ (1) | Ice Age: The Meltdown / 2006 | £1,100,736 |
| 2 | 16 Blocks / 2006 | £778,839 |
| 3↓ (2) | Silent Hill / 2006 | £683,147 |
| 4↓ (3) | Scary Movie 4 / 2006 | £544,138 |
| 5↓ (4) | American Dreamz / 2006 | £510,450 |
| 6 | Slither / 2006 | £488,446 |
| 7↑ (8) | Inside Man / 2006 | £310,606 |
| 8↓ (6) | She's the Man / 2006 | £290,676 |
| 9↓ (7) | Take the Lead / 2006 | £252,377 |
| 10↓ (5) | Eight Below / 2006 | £199,033 |
| 11↓ (9) | An American Haunting / 2006 | £180,797 |
| 12↓ (10) | Tristan + Isolde / 2006 | £129,192 |
| 13↑ (15) | The Squid and the Whale / 2005 | £65,814 |
| 14↓ (11) | The Shaggy Dog / 2006 | £63,557 |
| 15↓ (12) | The Mistress of Spices / 2006 | £59,216 |
| 16 | Freedomland / 2006 | £45,025 |
| 17↓ (16) | The White Countess / 2005 | £21,709 |
| 18↓ (17) | Deep Sea 3D / 2006 | £8,116 |
| 19 | The Amateurs / 2006 | £6,939 |
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