| Rank | Title | Weekend |
|---|---|---|
| 1 | The Omen / 2006 | £2,096,002 |
| 2↓ (1) | X-Men: The Last Stand / 2006 | £879,386 |
| 3↓ (2) | The Da Vinci Code / 2006 | £757,292 |
| 4↓ (3) | Poseidon / 2006 | £482,934 |
| 5↔ (5) | United 93 / 2006 | £337,829 |
| 6 | RV / 2006 | £273,850 |
| 7↓ (4) | The Wild / 2006 | £209,271 |
| 8 | Phir Hera Pheri / 2006 | £125,366 |
| 9↓ (6) | Mission:Impossible III / 2006 | £103,712 |
| 10↓ (8) | Fanaa / 2006 | £86,445 |
| 11 | Chup Chup Ke / 2006 | £79,246 |
| 12↓ (7) | Curious George / 2006 | £70,185 |
| 13↓ (12) | Friends With Money / 2006 | £28,873 |
| 14↓ (9) | Prime / 2006 | £22,507 |
| 15 | Secuestro Express / 2006 | £18,784 |
| 16 ⇅ (re) | Deep Sea 3D / 2006 | £6,754 |
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