| Rank | Title | Weekend |
|---|---|---|
| 1 | Yes Man / 2008 | £2,331,490 |
| 2 | Bedtime Stories / 2008 | £1,551,605 |
| 3 | Australia / 2008 | £1,294,414 |
| 4↓ (2) | Madagascar Escape 2 Africa / 2008 | £1,188,113 |
| 5↓ (1) | Twilight / 2008 | £1,153,607 |
| 6↓ (4) | The Day the Earth Stood Still / 2008 | £521,000 |
| 7 | Ghajini / 2008 | £318,538 |
| 8↓ (6) | Inkheart / 2008 | £310,374 |
| 9↓ (3) | Four Christmases / 2008 | £275,693 |
| 10↓ (5) | The Tale of Despereaux / 2008 | £240,043 |
| 11↓ (9) | Quantum of Solace / 2008 | £192,126 |
| 12↓ (7) | Rab Ne Bana Di Jodi / 2008 | £167,392 |
| 13↓ (8) | Changeling / 2008 | £142,253 |
| 14↓ (10) | Transporter 3 / 2008 | £75,972 |
| 15↓ (11) | A Bunch of Amateurs / 2008 | £29,718 |
| 16↓ (14) | High School Musical 3: Senior Year / 2008 | £15,912 |
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