| Rank | Title | Weekend |
|---|---|---|
| 1 | The Ugly Truth / 2009 | £1,976,043 |
| 2 | G.I. Joe: The Rise of Cobra / 2009 | £1,708,760 |
| 3↓ (1) | Harry Potter and the Half Blood Prince / 2009 | £1,349,113 |
| 4↓ (2) | G Force / 2009 | £1,223,891 |
| 5↓ (4) | The Proposal / 2009 | £755,242 |
| 6↓ (3) | The Taking of Pelham 123 / 2009 | £661,334 |
| 7↓ (5) | Ice Age: Dawn of the Dinosaurs / 2009 | £612,570 |
| 8 | Orphan / 2009 | £570,146 |
| 9↓ (8) | The Hangover / 2009 | £279,531 |
| 10↓ (9) | Coco Before Chanel / 2009 | £249,732 |
| 11↓ (7) | Brüno / 2009 | £203,853 |
| 12↓ (6) | Land of the Lost / 2009 | £186,567 |
| 13↓ (10) | Love Aaj Kal / 2009 | £161,493 |
| 14 | Mesrine Part 1: Killer Instinct / 2008 | £135,999 |
| 15↓ (12) | Moon / 2009 | £77,075 |
| 16 | Adam / 2009 | £23,201 |
| 17↓ (16) | Looking For Eric / 2009 | £2,548 |
| 18↑ (19) | Last Chance Harvey / 2008 | £2,413 |
| 19 | The Yes Men Fix the World / 2009 | £2,248 |
| 20↓ (17) | Skin / 2009 | £2,097 |
| 21↔ (21) | Mad Sad and Bad / 2009 | £544 |
| 22 | Mega Shark Vs. Giant Octopus / 2009 | £433 |
| 23 ⇅ (re) | The Young Victoria / 2009 | £331 |
| 24↔ (24) | The End of the Line / 2009 | £306 |
| 25 ⇅ (re) | Shifty / 2009 | £145 |
| 26 ⇅ (re) | In the Loop / 2009 | £104 |
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