| Rank | Title | Weekend |
|---|---|---|
| 1↑ (6) | Buster / 1988 | £1,035,954 |
| 2 | A Fish Called Wanda / 1988 | £1,018,700 |
| 3↓ (1) | Good Morning Vietnam / 1988 | £567,978 |
| 4↓ (2) | Midnight Run / 1988 | £282,110 |
| 5↓ (3) | The Running Man / 1988 | £87,075 |
| 6↓ (4) | Distant Voices, Still Lives / 1988 | £59,427 |
| 7↓ (5) | Poltergeist III / 1988 | £43,093 |
| 8↔ (8) | Big Business / 1988 | £17,940 |
| 9↓ (7) | Beetlejuice / 1988 | £14,718 |
| 10↔ (10) | Coming to America / 1988 | £10,891 |
| 11↓ (9) | Rambo III / 1988 | £7,191 |
| 12↑ (13) | The Last Temptation of Christ / 1988 | £2,979 |
| 13↑ (14) | Police Academy 5: Assignment Miami Beach / 1988 | £1,007 |
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