| Rank | Title | Weekend |
|---|---|---|
| 1↑ (2) | A Fish Called Wanda / 1988 | £718,594 |
| 2↓ (1) | Buster / 1988 | £717,977 |
| 3 | Big / 1988 | £716,688 |
| 4↓ (3) | Good Morning Vietnam / 1988 | £283,989 |
| 5↓ (4) | Midnight Run / 1988 | £112,844 |
| 6↓ (5) | The Running Man / 1988 | £45,829 |
| 7↓ (6) | Distant Voices, Still Lives / 1988 | £29,714 |
| 8↔ (8) | Big Business / 1988 | £11,213 |
| 9↔ (9) | Beetlejuice / 1988 | £10,451 |
| 10↔ (10) | Coming to America / 1988 | £8,712 |
| 11↔ (11) | Rambo III / 1988 | £3,269 |
| 12↔ (12) | The Last Temptation of Christ / 1988 | £1,089 |
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