| Rank | Title | Weekend |
|---|---|---|
| 1↔ (1) | Scary Movie / 2000 | £1,460,710 |
| 2↔ (2) | Snatch / 2000 | £1,097,240 |
| 3 | Shaft / 2000 | £872,545 |
| 4 | O Brother, Where Art Thou? / 2000 | £564,064 |
| 5 | The Cell / 2000 | £554,314 |
| 6↓ (3) | X-Men / 2000 | £413,909 |
| 7 | Keeping the Faith / 2000 | £261,887 |
| 8↓ (4) | Chicken Run / 2000 | £207,968 |
| 9↓ (5) | Stuart Little / 2000 | £200,336 |
| 10↓ (7) | Gone In 60 Seconds / 2000 | £69,793 |
| 11↓ (8) | Fiza / 2000 | £67,399 |
| 12↓ (6) | Shanghai Noon / 2000 | £62,379 |
| 13 | Dancer In the Dark / 2000 | £49,996 |
| 14↑ (15) | The Flintstones In Viva Rock Vegas / 2000 | £49,490 |
| 15↓ (10) | The Closer You Get / 2000 | £46,079 |
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