| Rank | Title | Weekend |
|---|---|---|
| 1 | Moulin Rouge / 2001 | £2,403,378 |
| 2 | Scary Movie 2 / 2001 | £1,553,796 |
| 3↓ (1) | A Knights Tale / 2001 | £1,000,190 |
| 4↓ (2) | Planet of the Apes / 2001 | £782,750 |
| 5↓ (3) | Cats & Dogs / 2001 | £495,615 |
| 6↓ (4) | Heartbreakers / 2001 | £339,690 |
| 7↓ (5) | Rush Hour 2 / 2001 | £310,469 |
| 8↓ (6) | Shrek / 2001 | £227,360 |
| 9↓ (8) | Crocodile Dundee In Los Angeles / 2001 | £187,171 |
| 10↓ (7) | Jurassic Park III / 2001 | £172,928 |
| 11↓ (10) | Dr. Dolittle 2 / 2001 | £132,108 |
| 12↓ (9) | Lucky Break / 2001 | £99,867 |
| 13↓ (12) | Swordfish / 2001 | £84,545 |
| 14↓ (13) | The Parole Officer / 2001 | £81,286 |
| 15↓ (14) | Lajja / 2001 | £77,574 |
| 16 | The Forsaken / 2001 | £13,075 |
| 17 | Startup.com / 2001 | £9,868 |
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