| Rank | Title | Weekend |
|---|---|---|
| 1↔ (1) | The Others / 2001 | £1,687,041 |
| 2↑ (3) | Legally Blonde / 2001 | £665,755 |
| 3↓ (2) | American Pie 2 / 2001 | £606,893 |
| 4 | Kiss of the Dragon / 2001 | £478,811 |
| 5↓ (4) | Jeepers Creepers / 2001 | £344,624 |
| 6↓ (5) | Atlantis: The Lost Empire / 2001 | £272,650 |
| 7↓ (6) | America's Sweethearts / 2001 | £233,390 |
| 8↔ (8) | Moulin Rouge / 2001 | £175,302 |
| 9↑ (10) | Amélie / 2001 | £159,301 |
| 10↓ (7) | The Animal / 2001 | £134,530 |
| 11↓ (9) | The Man Who Wasn't There / 2001 | £130,604 |
| 12 | The Piano Teacher / 2001 | £71,911 |
| 13↓ (11) | Enigma / 2001 | £55,268 |
| 14↓ (12) | Ashoka the Great / 2001 | £44,511 |
| 15↓ (14) | The Pledge / 2001 | £40,437 |
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