| Rank | Title | Weekend |
|---|---|---|
| 1 | Harry Potter and the Philosopher's Stone / 2001 | £16,335,627 |
| 2↓ (1) | The Others / 2001 | £1,315,412 |
| 3↓ (2) | Legally Blonde / 2001 | £516,813 |
| 4↓ (3) | American Pie 2 / 2001 | £421,284 |
| 5↓ (4) | Kiss of the Dragon / 2001 | £296,870 |
| 6↓ (5) | Jeepers Creepers / 2001 | £198,750 |
| 7↓ (6) | Atlantis: The Lost Empire / 2001 | £162,316 |
| 8↑ (9) | Amélie / 2001 | £142,448 |
| 9 | Ghost World / 2001 | £133,188 |
| 10↓ (8) | Moulin Rouge / 2001 | £121,590 |
| 11↓ (7) | America's Sweethearts / 2001 | £119,286 |
| 12↓ (11) | The Man Who Wasn't There / 2001 | £75,897 |
| 13↓ (10) | The Animal / 2001 | £62,844 |
| 14↓ (12) | The Piano Teacher / 2001 | £48,858 |
| 15↓ (13) | Enigma / 2001 | £27,517 |
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