| Rank | Title | Weekend |
|---|---|---|
| 1↔ (1) | Harry Potter and the Philosopher's Stone / 2001 | £8,362,749 |
| 2 | Spy Game / 2001 | £1,019,847 |
| 3↓ (2) | The Others / 2001 | £975,464 |
| 4↓ (3) | Legally Blonde / 2001 | £388,549 |
| 5↓ (4) | American Pie 2 / 2001 | £256,071 |
| 6↓ (5) | Kiss of the Dragon / 2001 | £156,321 |
| 7↔ (7) | Atlantis: The Lost Empire / 2001 | £122,716 |
| 8↔ (8) | Amélie / 2001 | £101,159 |
| 9 | Heist / 2001 | £100,229 |
| 10↓ (9) | Ghost World / 2001 | £100,152 |
| 11↓ (6) | Jeepers Creepers / 2001 | £89,353 |
| 12↓ (10) | Moulin Rouge / 2001 | £74,201 |
| 13 | Baby Boy / 2001 | £47,144 |
| 14 | Me Without You / 2001 | £45,532 |
| 15↓ (11) | America's Sweethearts / 2001 | £44,797 |
| 16 | Glitter / 2001 | £14,925 |
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