| Rank | Title | Weekend |
|---|---|---|
| 1↔ (1) | Ice Age: The Meltdown / 2006 | £3,608,531 |
| 2 | Scary Movie 4 / 2006 | £1,953,094 |
| 3↑ (4) | Inside Man / 2006 | £639,641 |
| 4 | Take the Lead / 2006 | £621,735 |
| 5↓ (2) | She's the Man / 2006 | £599,968 |
| 6 | An American Haunting / 2006 | £541,446 |
| 7↓ (3) | Alien Autopsy / 2006 | £315,661 |
| 8↓ (5) | Failure to Launch / 2006 | £206,984 |
| 9↓ (7) | The Shaggy Dog / 2006 | £191,849 |
| 10 | Humko Deewana Kar Gaye / 2006 | £174,934 |
| 11↓ (6) | Hostel / 2006 | £159,870 |
| 12↓ (9) | The Pink Panther / 2006 | £135,972 |
| 13↓ (12) | Yours, Mine & Ours / 2006 | £90,821 |
| 14↑ (15) | The White Countess / 2005 | £73,152 |
| 15↑ (16) | The Squid and the Whale / 2005 | £69,438 |
| 16↓ (8) | The Dark / 1993 | £66,203 |
| 17↑ (20) | The Ballad of Jack and Rose / 2005 | £4,365 |
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