| Rank | Title | Weekend |
|---|---|---|
| 1↔ (1) | Happy Feet / 2006 | £2,034,916 |
| 2↔ (2) | The Holiday / 2006 | £1,597,633 |
| 3↔ (3) | Casino Royale / 2006 | £1,440,607 |
| 4 | Eragon / 2006 | £1,317,687 |
| 5 | Déjà Vu / 2006 | £1,098,295 |
| 6↓ (4) | Flushed Away / 2006 | £783,684 |
| 7↓ (5) | The Santa Clause 3: The Escape Clause / 2006 | £555,099 |
| 8 | Black Christmas / 2006 | £367,743 |
| 9 | Grounded: Unaccompanied Minors / 2006 | £240,378 |
| 10↓ (6) | Deck the Halls / 2006 | £178,514 |
| 11↓ (8) | Baabul / 2006 | £168,653 |
| 12↓ (7) | Borat: Cultural Learnings of America For Make Benefit Glorious Nation of Kazakhstan / 2006 | £144,368 |
| 13↓ (10) | Pans Labyrinth / 2006 | £126,873 |
| 14 | Kabul Express / 2006 | £49,928 |
| 15↓ (11) | Stranger Than Fiction / 2006 | £41,685 |
| 16↔ (16) | London to Brighton / 2006 | £14,204 |
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