| Rank | Title | Weekend |
|---|---|---|
| 1 | Trolls / 2016 | £5,440,878 |
| 2 | Jack Reacher Never Go Back / 2016 | £2,688,561 |
| 3↓ (1) | The Girl On the Train / 2016 | £1,996,858 |
| 4↓ (2) | Inferno / 2016 | £1,297,969 |
| 5↔ (5) | Bridget Jones's Baby / 2016 | £1,123,971 |
| 6 | Ouija: Origin of Evil / 2016 | £779,626 |
| 7↓ (6) | Miss Peregrines Home For Peculiar Children / 2016 | £736,177 |
| 8↓ (3) | Storks / 2016 | £668,760 |
| 9 | I, Daniel Blake / 2016 | £444,800 |
| 10 | Keeping Up With the Joneses / 2016 | £271,306 |
| 11 | Don Giovanni: Met Opera 2016 / 2016 | £254,469 |
| 12↓ (7) | Deepwater Horizon / 2016 | £148,110 |
| 13↓ (12) | The Secret Life of Pets / 2016 | £104,807 |
| 14↓ (9) | Finding Dory / 2016 | £79,966 |
| 15↔ (15) | The BFG / 2016 | £76,541 |
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