| Directed by | ||
|---|---|---|
 | Bill Condon | |
| Starring | ||
|---|---|---|
 | Ian McKellen | Sherlock Holmes |
 | Laura Linney | Mrs. Munro |
| Milo Parker | Roger |
| Hiroyuki Sanada | Tamiki Umezaki |
| Hattie Morahan | Ann Kelmot |
| Patrick Kennedy | Thomas Kelmot |
| Roger Allam | Dr. Barrie |
| Phil Davis | Inspector Gilbert |
| Frances de la Tour | Madame Schirmer |
| Charles Maddox | Oswald |
| Takako Akashi | Maya Umezaki |
| Zak Shukor | Masuo Umezaki |
| John Sessions | Mycroft Holmes |
| Michael Culkin | Bank Manager |
| David Foxxe | Chemist |
| Oliver Devoti | Ticket Agent |
| Mike Burnside | Ann's Solicitor |
| Nicholas Rowe | Matinee 'Sherlock Holmes' |
| Sam Coulson | Matinee 'Thomas Kelmot' |
| Frances Barber | Matinee 'Madame Schirmer' |
 | Hermione Corfield | Matinee 'Ann Kelmot' |
| Kit Connor | Boy |
| Zoe Rainey | Boy's Mother |
| Eileen Davies | Lady on Platform |
| Colin Starkey | Dr. John Watson |
| Sarah Crowden | Mrs. Hudson |
| Claire Ashton | Bookshop Customer |
| Paul Blackwell | Station Passenger |
| Sal Bolton | Passer by / Sherlockian |
| John Carr | Patron in Cinema |
| Elizabeth Jane Cassidy | Waitress |
| Siong Loong Choong | Japanese Peasant |
| Gioacchino Jim Cuffaro | Passer by |
| John Duggan | Bookshop patron |
| Sam Exley | Stone Mason |
| Ben Farrow | Bank Clerk |
| Marina Hayter | Passerby |
| Tula Howarth | Extra |
| Paul Kerry | Cinema Attendee |
| Helen Kingston | Cafe Customer |
| Rogers Leona | Lady on Train |
| Devlin Lloyd | Sherlockian / Cinema Attendee |
| Shaun Lucas | Passerby in garden |
| Sonia Mason | Passenger (Mother) |
| Siobhan McSweeney | Una Gilbert |
| Keith Milner | Postman |
| Shina Shihoko Nagai | Japanese Middle Class / Serving Staff |
| Karl Ng | Japanese Porter |
| Jason Nicholls | 1919 Gent / 1947 Cinema Goer |
| Eitetsu Nozawa | Wandering Monk / Market Foreman |
| Johnny Otto | Army Officer |
| Tony Pankhurst | Police Sargeant |
| Tom Patrick | Tea Shop Customer |
| Jason Saunders | Private club Gentleman |
| Linus Scheithauer | Baggage Handler / Ticket Tearer |
| Robert Scott | Passer by |
| Dean Sills | Passer-by |
| Clem So | Japanese Customer |
| Colin Taylor | Village Resident |
| Mark Underwood | Maitre d' |
| Nathan Webb | Paramedic |
| Spike White | Joe Gilbert |
| Madeleine Worrall | The Haunted Woman |
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