| Rank | Title | Weekend |
|---|---|---|
| 1 | X-Men: First Class / 2011 | £5,438,386 |
| 2↓ (1) | The Hangover Part II / 2011 | £3,826,158 |
| 3↓ (2) | Pirates of the Caribbean: On Stranger Tides / 2011 | £2,144,179 |
| 4↓ (3) | Diary of a Wimpy Kid: Rodrick Rules / 2011 | £645,196 |
| 5 | JLS: Eyes Wide Open / 2011 | £463,914 |
| 6 | Senna / 2011 | £375,173 |
| 7 | Ready / 2011 | £236,868 |
| 8↓ (6) | Rio / 2011 | £94,127 |
| 9↓ (5) | Fast Five / 2011 | £77,874 |
| 10↓ (4) | Thor / 2011 | £59,994 |
| 11 | Last Night / 2011 | £51,245 |
| 12↓ (7) | Insidious / 2011 | £45,554 |
| 13↓ (10) | Water For Elephants / 2011 | £38,588 |
| 14↓ (8) | Hanna / 2011 | £35,863 |
| 15 | Prom / 2011 | £34,885 |
| 16↓ (9) | Attack the Block / 2011 | £19,272 |
| 17↓ (16) | TT3D: Closer to the Edge / 2011 | £16,640 |
| 18 | Mammuth / 2011 | £12,657 |
| 19 | Jak Sie Pozbyc Cellulitu / 2011 | £10,663 |
| 20 | Screwed / 2011 | £9,297 |
| 21↓ (19) | Fire In Babylon / 2011 | £5,971 |
| 22↓ (11) | Blitz / 2011 | £4,482 |
| 23↑ (24) | Jig / 2011 | £3,635 |
| 24↓ (23) | The King's Speech / 2010 | £1,671 |
| 25 | Rio Breaks / 2011 | £1,616 |
| 26↓ (22) | Submarine / 2011 | £1,545 |
| 27↓ (21) | Oranges and Sunshine / 2011 | £522 |
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