| Rank | Title | Weekend |
|---|---|---|
| 1 | Kung-Fu Panda 2 / 2011 | £6,188,897 |
| 2↔ (2) | The Hangover Part II / 2011 | £2,759,846 |
| 3↓ (1) | X-Men: First Class / 2011 | £2,401,492 |
| 4↓ (3) | Pirates of the Caribbean: On Stranger Tides / 2011 | £1,580,778 |
| 5 | Honey 2 / 2011 | £520,654 |
| 6↓ (4) | Diary of a Wimpy Kid: Rodrick Rules / 2011 | £455,239 |
| 7↓ (6) | Senna / 2011 | £408,923 |
| 8↓ (7) | Ready / 2011 | £114,878 |
| 9 | Mother's Day / 2011 | £94,384 |
| 10↓ (8) | Rio / 2011 | £65,682 |
| 11 ⇅ (re) | Winnie the Pooh / 2011 | £47,370 |
| 12 | Point Blank / 2011 | £43,021 |
| 13↓ (9) | Fast Five / 2011 | £35,278 |
| 14↔ (14) | Hanna / 2011 | £31,769 |
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