| Directed by | ||
|---|---|---|
 | Dan Ireland | |
| Starring | ||
|---|---|---|
 | Harry Connick Jr. | Dr. Dennis Slamon |
| Tammy Blanchard | Nicole Wilson |
| Amanda Bynes | Jamie McGrath |
| Jennifer Coolidge | Tish |
| Angie Harmon | Lilly Tartikoff |
| John Benjamin Hickey | Blake Rogers |
 | Regina King | Ellie Jackson |
| Swoosie Kurtz | Elizabeth |
| Paula Cale | Donna Slamon |
| Amy Madigan | Fran Visco |
| Bernadette Peters | Barbara Bradfield |
| Trudie Styler | Tina |
| Bruce McKinnon | Dean Bradfield |
| Jackson Hurst | Josh |
| Tom Nowicki | Carl Reinhardt |
| Brandon Smith | Pharmacy Board Member |
| William Ragsdale | Andy Marks |
| Naima Lett | Nurse Carol |
| Griff Furst | Charlie Wilson |
| Maria Howell | Kate |
| Joe Nemmers | Ron Perelman |
| Rhoda Griffis | Bindy Blake |
| J. Patrick McNamara | Dr. Rice |
| Lance E. Nichols | Dr. Brown |
| Louis Herthum | Dr. Banks |
| Kim Wall | Marci |
| Melissa McBride | Sally |
| Connor Hill | Sam Wilson Age 5 |
| Tyler Case | Sam Wilson Age 7 and 8 |
| Cooper Cason | Sam Wilson Age 14 |
| Sophia Watson | Joey Lyn Slamon Age 7 |
| Abby Rao | Joey Lyn Slamon Age 9 |
| Sam Richardson | Matt Slamon Age 3 - 5 |
| Ben Lux | Matt Slamon Age 7 |
| Austin Lux | Matt Slamon Age 9 |
| Elliott Grey | Board Member |
| Andrew Matthews | Darrin Bradfield |
| Evan Gamble | Peter Wilson |
| Shanna Forrestall | Runner #2 |
| Jessica Lucas | Runner #3 |
| Joshua Wells | Medical Intern |
| Julia Adams | Jogger |
| Garrett Allain | Nurse |
| Heather A. Allen | Jogger |
| Natasha "Sasha" Angelety | |
| Barbara Balentine | Cancer Patient |
| Allen Boudreaux | Executive |
| Dane Brown | Doctor |
| Joanna Doherty | Diner |
| Debby Gaudet | Laboratory Technician |
| Sabrita Gordon | Cancer Patient |
| Russell M. Haeuser | Hospital Maintence Worker |
| Rhonda Huete | Track and Field Spectator |
| Victor Eli Hugo | U.C.L.A. Student |
| Vianca Johnson | College Student |
| Topher Jones | College Student |
| Angela Kozak | Restaurant Patron |
| Seth Kozak | Peter Hawn |
| Rhonda Laizer | Medical Professor |
| Rose Lamarche | Hospital Patient |
| Laurie Lee | Cancer Patient / Hospital Visitor / Cancer Walk Participant |
| Audrey Lynn | Woman |
| Jay Oliver | Lab Tech |
| Holly Rochelle | Red Carpet Photographer |
| Scott Schlueter | Delivery Guy / Laboratory Technician |
| Codie Scott | Dinning Husband |
| Sean M. Sellers | Bartender |
| Chaz Smith | Laboratory Technician |
| Logan Douglas Smith | Surgeon |
| Antoine Spillers | U.C.L.A. Student |
| Corey Stewart | College Student |
| Sarah J. Thompson | Student |
| Jeremy Dean Turner | Restaurant Patron / Fire and Ice Attendee |
| Daniel Woods | Waiter |
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