| Directed by | ||
|---|---|---|
 | Michael Showalter | |
| Starring | ||
|---|---|---|
 | Kumail Nanjiani | Kumail |
 | Zoe Kazan | Emily |
| Holly Hunter | Beth |
 | Ray Romano | Terry |
| Anupam Kher | Azmat |
| Zenobia Shroff | Sharmeen |
| Adeel Akhtar | Naveed |
| Bo Burnham | CJ |
| Aidy Bryant | Mary |
| Kurt Braunohler | Chris |
| Vella Lovell | Khadija |
| Myra Lucretia Taylor | Nurse Judy |
| Jeremy Shamos | Bob Dalavan |
| David Alan Grier | Andy Dodd |
| Ed Herbstman | Sam Highsmith |
| Shenaz Treasury | Fatima |
| Rebecca Naomi Jones | Jesse |
| Kuhoo Verma | Zubeida |
| Mitra Jouhari | Yazmin |
| Celeste Arias | Denise |
| Shana Solomon | Nurse Bette |
| Jeff Blumenkrantz | Dr. Wright |
| Linda Emond | Dr. Cunningham |
| Holly Chou | Dr. Whelan |
| Andrew Pang | Dr. Spellman |
| Alison Cimmet | Dr. Platt |
| Lawrence Ballard | Dr. Lewin |
| Shunori Ramanathan | Sumera |
| Spencer House | Racist Heckler |
| Susham Bedi | Tina (Khadija's Mother) |
| Rahul Bedi | Farhan (Khadija's Father) |
| Matty Cardarople | Fast Food Cashier |
| Myra Turley | Waiting Room Person 1 |
| William Stephenson | Waiting Room Person 2 |
| Marilyn Torres | Waiting Room Person 3 |
| Kerry Flanagan | Waiting Room Person 4 |
| Jack O'Connell | |
| Charles Gould | Waiting Room Person 6 |
| Isabel Shill | Party Goer 1 |
| Lauren Patten | Party Goer 2 |
| Keilly McQuail | Party Goer 3 |
| Zach Cherry | Party Goer 4 |
| Jack Corrigan | Restaurant Boy |
| Stephanie DiFiore | Bethany |
| Amanda Glaze | Kumail's Uber Passenger Staring at Phone |
| Emily V. Gordon | Woman Next to CJ at Kumail's Final Gig |
| Sophia Muller | Chrissy |
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